The Bocarsly lab uses a systems level approach to identify the neural substrates, circuits, and behavioral motivations driving food intake and their contributions to the development of disease states such as compulsive overeating, obesity, and anorexia. To do this, the laboratory uses a combination of novel transgenic mouse lines, optogenetics, chemogenetics, in vivo fiber photometry, molecular techniques, ex vivo brain slice fast-scan cyclic voltammetry, and fiber photometry, as well as behavior using mouse models.